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Mis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induced by Albuminuria in Proximal Tubules

High albumin concentrations in the proximal tubule of the kidney causes tubulointerstitial injury, but how this process occurs is not completely known. To address the signal transduction pathways mis-regulated in renal injury, we studied the modulation of mammalian target of rapamycin (mTOR) complex...

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Bibliographic Details
Main Authors: Peruchetti, Diogo B., Cheng, Jie, Caruso-Neves, Celso, Guggino, William B.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059122/
https://ncbi.nlm.nih.gov/pubmed/24790108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549717
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