Sputum Hyaluronan and Versican in Severe Eosinophilic Asthma

BACKGROUND: We examined levels of hyaluronan, a matrix glycosaminoglycan and versican, a matrix proteoglycan, in the sputum of asthmatics treated with mepolizumab (anti-IL-5 mAb) versus placebo to evaluate the utility of these measurements as possible biomarkers of asthma control and airway remodeli...

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Bibliografiske detaljer
Main Authors: Ayars, Andrew G, Altman, Leonard C, Potter-Perigo, Sue, Radford, Katherine, Wight, Thomas N, Nair, Parameswaran
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059000/
https://ncbi.nlm.nih.gov/pubmed/23257685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343031
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