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The interaction of the ErbB4 intracellular domain p80 with α-enolase in the nuclei is associated with the inhibition of the neuregulin1-dependent cell proliferation

We have shown that the receptor tyrosine kinase ErbB4 signals neuregulin1-stimulated proliferation of human cells. Some isoforms of ErbB4 are cleaved to release the soluble intracellular domain p80; however, the function of p80 in cell proliferation remained unclear. Here we propose the possibility...

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Detalhes bibliográficos
Main Authors: Yamada, Satomi, Marutsuka, Masaki, Inoue, Miyabi, Zhang, Jidong, Abe, Shin-ichi, Ishibashi, Ken-ichi, Yamaguchi, Naoto, Eto, Ko
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058961/
https://ncbi.nlm.nih.gov/pubmed/24955285
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