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AlignGraph: algorithm for secondary de novo genome assembly guided by closely related references

Motivation: De novo assemblies of genomes remain one of the most challenging applications in next-generation sequencing. Usually, their results are incomplete and fragmented into hundreds of contigs. Repeats in genomes and sequencing errors are the main reasons for these complications. With the rapi...

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Autors principals: Bao, Ergude, Jiang, Tao, Girke, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058956/
https://ncbi.nlm.nih.gov/pubmed/24932000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu291
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