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Challenges in the Pharmacogenomic Annotation of Whole Genomes

Next-generation sequencing technologies have enabled the sequencing of an entire genome for less than $4,000. With access to all the genetic variation in an individual, our task will be to use this information to assess the genetic influences on drug efficacy, toxicity, and dosage.

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Detalhes bibliográficos
Main Authors: Altman, RB, Whirl-Carrillo, M, Klein, TE
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058909/
https://ncbi.nlm.nih.gov/pubmed/23708745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.111
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