Intermittent hypoxia-induced protein phosphatase 2A activation reduces PC12 cell proliferation and differentiation

BACKGROUND: Intermittent hypoxia (IH) plays a critical role in sleep breathing disorder-associated hippocampus impairments, including neurocognitive deficits, irreversible memory and learning impairments. IH-induced neuronal injury in the hippocampus may result from reduced precursor cell proliferat...

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Autors principals: Chen, Tsung-I, Chiu, Hung-Wen, Pan, Yi-Chung, Hsu, Shih-Ting, Lin, Jian-Hong, Yang, Kun-Ta
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058715/
https://ncbi.nlm.nih.gov/pubmed/24885237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-46
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