The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa

BACKGROUND: Retinitis pigmentosa (RP) is an inherited human retinal disorder that causes progressive photoreceptor cell loss, leading to severe vision impairment or blindness. However, no effective therapy has been established to date. Although genetic mutations have been identified, the available c...

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Detalhes bibliográficos
Main Authors: Yoshida, Tetsu, Ozawa, Yoko, Suzuki, Keiichiro, Yuki, Kenya, Ohyama, Manabu, Akamatsu, Wado, Matsuzaki, Yumi, Shimmura, Shigeto, Mitani, Kohnosuke, Tsubota, Kazuo, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058693/
https://ncbi.nlm.nih.gov/pubmed/24935155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-45
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