In Vitro Inhibition of Hepatitis C Virus by Antisense Oligonucleotides in PBMC Compared to Hepatoma Cells

Aim. To assess the efficiency of phosphorothioate antisense oligodeoxynucleotide 1 (S-ODN1) on HCV translation inhibition in PBMC compared to hepatoma cells in vitro for the first time. Materials and Methods. The study included 34 treatment naive HCV patients. IRES domain III and IV sequence variati...

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Main Authors: Youssef, Samar Samir, Fahmy, Ahmed Mohamed, Omran, Moataza Hassan, Mohamed, Amr Saad, El Desouki, Mohamed Ali, El-Awady, Mostafa K.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058683/
https://ncbi.nlm.nih.gov/pubmed/24991538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/196712
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