Inhibition of 5-Lipoxygenase Pathway Attenuates Acute Liver Failure by Inhibiting Macrophage Activation

This study aimed to investigate the role of 5-lipoxygenase (5-LO) in acute liver failure (ALF) and changes in macrophage activation by blocking it. ALF was induced in rats by administration of D-galactosamine (D-GalN)/lipopolysaccharide (LPS). Rats were injected intraperitoneally with AA-861 (a spec...

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Autors principals: Li, Lu, Liu, Yi-Rong, Gao, Shan, Li, Jun-Feng, Li, Shan-Shan, Zhang, Dan-Dan, Liu, Shuang, Bai, Li, Zheng, Su-Jun, Duan, Zhong-Ping, Qi, Min, Chen, Yu
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058580/
https://ncbi.nlm.nih.gov/pubmed/24987711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/697560
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