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Evolution of acquired resistance to anti-cancer therapy

Acquired drug resistance is a major limitation for the successful treatment of cancer. Resistance can emerge due to a variety of reasons including host environmental factors as well as genetic or epigenetic alterations in the cancer cells. Evolutionary theory has contributed to the understanding of...

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Detalhes bibliográficos
Main Authors: Foo, Jasmine, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058397/
https://ncbi.nlm.nih.gov/pubmed/24681298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.02.025
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