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Candidate chromosome 1 disease susceptibility genes for Sjogren’s syndrome xerostomia are narrowed by novel NOD.B10 congenic mice

Sjogren’s syndrome (SS) is characterized by salivary gland leukocytic infiltrates and impaired salivation (xerostomia). Cox-2 (Ptgs2) is located on chromosome 1 within the span of the Aec2 region. In an attempt to demonstrate that COX-2 drives antibody-dependent hyposalivation, NOD.B10 congenic mice...

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Detalhes bibliográficos
Main Authors: Mongini, Patricia K. A., Kramer, Jill M., Ishikawa, Tomo-o, Herschman, Harvey, Esposito, Donna
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058348/
https://ncbi.nlm.nih.gov/pubmed/24685748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.03.012
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