IFN-γ-Secreting-Mesenchymal Stem Cells Exert an Antitumor Effect In Vivo via the TRAIL Pathway

Mesenchymal stem cells (MSCs) can exhibit either prooncogenic or antitumor properties depending on the context. Based on our previous study, we hypothesized that MSCs engineered to deliver IFN-γ would kill cancer cells through persistent activation of the TRAIL pathway. Human bone-marrow (BM-) deriv...

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Detalhes bibliográficos
Main Authors: Yang, Xinyuan, Du, Jingchun, Xu, Xia, Xu, Chun, Song, Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058226/
https://ncbi.nlm.nih.gov/pubmed/24971369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/318098
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