IFN-γ-Secreting-Mesenchymal Stem Cells Exert an Antitumor Effect In Vivo via the TRAIL Pathway

Mesenchymal stem cells (MSCs) can exhibit either prooncogenic or antitumor properties depending on the context. Based on our previous study, we hypothesized that MSCs engineered to deliver IFN-γ would kill cancer cells through persistent activation of the TRAIL pathway. Human bone-marrow (BM-) deriv...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yang, Xinyuan, Du, Jingchun, Xu, Xia, Xu, Chun, Song, Wu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058226/
https://ncbi.nlm.nih.gov/pubmed/24971369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/318098
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