Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability

The cancer chemopreventive property of Chinese herb new isolate isorhapontigenin (ISO) and mechanisms underlying its activity have never been explored. Here we demonstrated that ISO treatment with various concentrations for 3 weeks could dramatically inhibit TPA/EGF-induced cell transformation of Cl...

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Sonraí Bibleagrafaíochta
Main Authors: Gao, Guangxun, Chen, Liang, Li, Jingxia, Zhang, Dongyun, Fang, Yong, Huang, Haishan, Chen, Xiequn, Huang, Chuanshu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2014
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058035/
https://ncbi.nlm.nih.gov/pubmed/24797581
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