Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability

The cancer chemopreventive property of Chinese herb new isolate isorhapontigenin (ISO) and mechanisms underlying its activity have never been explored. Here we demonstrated that ISO treatment with various concentrations for 3 weeks could dramatically inhibit TPA/EGF-induced cell transformation of Cl...

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Detalhes bibliográficos
Main Authors: Gao, Guangxun, Chen, Liang, Li, Jingxia, Zhang, Dongyun, Fang, Yong, Huang, Haishan, Chen, Xiequn, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058035/
https://ncbi.nlm.nih.gov/pubmed/24797581
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