Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability

The cancer chemopreventive property of Chinese herb new isolate isorhapontigenin (ISO) and mechanisms underlying its activity have never been explored. Here we demonstrated that ISO treatment with various concentrations for 3 weeks could dramatically inhibit TPA/EGF-induced cell transformation of Cl...

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Autors principals: Gao, Guangxun, Chen, Liang, Li, Jingxia, Zhang, Dongyun, Fang, Yong, Huang, Haishan, Chen, Xiequn, Huang, Chuanshu
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058035/
https://ncbi.nlm.nih.gov/pubmed/24797581
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