The Peroxisome Proliferator-Activated Receptor (PPAR) α Agonist Fenofibrate Suppresses Chemically Induced Lung Alveolar Proliferative Lesions in Male Obese Hyperlipidemic Mice

Activation of peroxisome proliferator-activated receptor (PPAR) α disrupts growth-related activities in a variety of human cancers. This study was designed to determine whether fenofibrate, a PPARα agonist, can suppress 4-nitroquinoline 1-oxide (4-NQO)-induced proliferative lesions in the lung of ob...

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Main Authors: Kuno, Toshiya, Hata, Kazuya, Takamatsu, Manabu, Hara, Akira, Hirose, Yoshinobu, Takahashi, Satoru, Imaida, Katsumi, Tanaka, Takuji
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057781/
https://ncbi.nlm.nih.gov/pubmed/24857924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15059160
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