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Topical N-Acetylcysteine Accelerates Wound Healing in Vitro and in Vivo via the PKC/Stat3 Pathway

N-Acetylcysteine (Nac) is an antioxidant administered in both oral and injectable forms. In this study, we used Nac topically to treat burn wounds in vitro and in vivo to investigate mechanisms of action. In vitro, we monitored glutathione levels, cell proliferation, migration, scratch-wound healing...

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Detalhes bibliográficos
Main Authors: Tsai, Min-Ling, Huang, Hui-Pei, Hsu, Jeng-Dong, Lai, Yung-Rung, Hsiao, Yu-Ping, Lu, Fung-Jou, Chang, Horng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057691/
https://ncbi.nlm.nih.gov/pubmed/24798751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15057563
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