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Evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models

To date, plants have been the major source of anticancer drugs. Boldine is a natural alkaloid commonly found in the leaves and bark of Peumus boldus. In this study, we found that boldine potently inhibited the viability of the human invasive breast cancer cell lines, MDA-MB-231 (48-hour IC(50) 46.5±...

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Detalhes bibliográficos
Main Authors: Paydar, Mohammadjavad, Kamalidehghan, Behnam, Wong, Yi Li, Wong, Won Fen, Looi, Chung Yeng, Mustafa, Mohd Rais
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057328/
https://ncbi.nlm.nih.gov/pubmed/24944509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S58178
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