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Increased Growth-Inhibitory and Cytotoxic Activity of Arsenic Trioxide in Head and Neck Carcinoma Cells with Functional p53 Deficiency and Resistance to EGFR Blockade

BACKGROUND AND PURPOSE: Mutations in the p53 gene are frequently observed in squamous cell carcinoma of the head and neck region (SCCHN) and have been associated with drug resistance. The potential of arsenic trioxide (ATO) for treatment of p53-deficient tumor cells and those with acquired resistanc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Boyko-Fabian, Mariya, Niehr, Franziska, Distel, Luitpold, Budach, Volker, Tinhofer, Ingeborg
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057125/
https://ncbi.nlm.nih.gov/pubmed/24927258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098867
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