RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells

Asthma is a chronic inflammatory respiratory disease that affects over 300 million people worldwide. Glucocorticoids are a mainstay therapy for asthma because they exert anti-inflammatory effects in multiple lung tissues, including the airway smooth muscle (ASM). However, the mechanism by which gluc...

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Autori principali: Himes, Blanca E., Jiang, Xiaofeng, Wagner, Peter, Hu, Ruoxi, Wang, Qiyu, Klanderman, Barbara, Whitaker, Reid M., Duan, Qingling, Lasky-Su, Jessica, Nikolos, Christina, Jester, William, Johnson, Martin, Panettieri, Reynold A., Tantisira, Kelan G., Weiss, Scott T., Lu, Quan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057123/
https://ncbi.nlm.nih.gov/pubmed/24926665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099625
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