TRAIL Enhances Apoptosis of Human Hepatocellular Carcinoma Cells Sensitized by Hepatitis C Virus Infection: Therapeutic Implications

Hepatitis C virus (HCV) infection causes chronic liver diseases leading to hepatocellular carcinoma (HCC) and liver failure. We have previously shown that HCV sensitizes hepatocytes to mitochondrial apoptosis via the TRAIL death receptors DR4 and DR5. Although TRAIL and its receptors are selective t...

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Détails bibliographiques
Auteurs principaux: Jang, Jae Young, Kim, Seong-Jun, Cho, Eun Kyung, Jeong, Soung Won, Park, Eui Ju, Lee, Woong Cheul, Lee, Sae Hwan, Kim, Sang Gyune, Kim, Young Seok, Kim, Hong Soo, Kim, Boo Sung, Lin, Wenyu, Chung, Raymond T.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057066/
https://ncbi.nlm.nih.gov/pubmed/24927176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098171
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