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3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease

[Image: see text] Several 3-hydroxyquinolin-2(1H)-ones derivatives were synthesized and evaluated as inhibitors of 2009 pandemic H1N1 influenza A endonuclease. All five of the monobrominated 3-hydroxyquinolin(1H)-2-ones derivatives were synthesized. Suzuki-coupling of p-fluorophenylboronic acid with...

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Détails bibliographiques
Auteurs principaux: Sagong, Hye Yeon, Parhi, Ajit, Bauman, Joseph D., Patel, Disha, Vijayan, R. S. K., Das, Kalyan, Arnold, Eddy, LaVoie, Edmond J.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2013
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056971/
https://ncbi.nlm.nih.gov/pubmed/24936242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4001112
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