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Platelet mitochondrial membrane depolarization reflects disease severity in patients with sepsis and correlates with clinical outcome

INTRODUCTION: Sepsis is still a leading cause of morbidity and mortality, even in modern times, and thrombocytopenia has been closely associated with unfavorable disease outcome. Decreases in mitochondrial membrane potential (depolarization) were found in different tissues during sepsis. Previous wo...

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Detalhes bibliográficos
Main Authors: Gründler, Katharina, Angstwurm, Matthias, Hilge, Robert, Baumann, Philipp, Annecke, Thorsten, Crispin, Alexander, Sohn, Hae-Young, Massberg, Steffen, Kraemer, Bjoern F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056796/
https://ncbi.nlm.nih.gov/pubmed/24521521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13724
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