COMP-angiopoietin-1 enhances skeletal muscle blood flow and insulin sensitivity in mice

To test whether chronic enhanced blood flow alters insulin-stimulated glucose uptake, we measured skeletal muscle glucose uptake in chow-fed and high-fat-fed mice injected with adenovirus containing modified angiopoietin-1, COMP-Ang1, via euglycemic-hyperinsulinemic clamp. Blood flow rates and plate...

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Main Authors: Sung, Hoon Ki, Kim, Yong-Woon, Choi, Soo Jeong, Kim, Jong-Yeon, Jeune, Kyung Hee, Won, Kyu-Chang, Kim, Jason K., Koh, Gyu Young, Park, So-Young
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056742/
https://ncbi.nlm.nih.gov/pubmed/19491299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00122.2009
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