Transcriptional Regulation of the Albumin Gene Depends on the Removal of Histone Methylation Marks by the FAD-Dependent Monoamine Oxidase Lysine-Specific Demethylase 1 in HepG2 Human Hepatocarcinoma Cells(1)(2)(3)

Lysine-specific demethylase (LSD) 1 is an FAD-dependent demethylase that catalyzes the removal of methyl groups from lysine-4 in histone H3, thereby mediating gene repression. Here we tested the hypothesis that riboflavin deficiency causes a loss of LSD1 activity in HepG2 human hepatocarcinoma cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Dandan, Zempleni, Janos
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Nutrition 2014
Konular:
Biochemical, Molecular, and Genetic Mechanisms
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056651/
https://ncbi.nlm.nih.gov/pubmed/24744315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.114.192187
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