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AZD-3043: A Novel, Metabolically-Labile Sedative/Hypnotic Agent with Rapid and Predictable Emergence from Hypnosis
BACKGROUND: Propofol can be associated with delayed awakening after prolonged infusion. The aim of this study was to characterize the preclinical pharmacology of AZD-3043, a positive allosteric modulator of the γ-aminobutyric acid(A) (GABA(A)) receptor containing a metabolically-labile ester moiety....
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056591/ https://ncbi.nlm.nih.gov/pubmed/22531340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31825685a6 |
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