The angiotensin II AT1 receptor-associated protein Arap1 is involved in sepsis-induced hypotension

INTRODUCTION: Hypotension in septic patients results from hypovolemia, vasodilatation and hyporeactivity to vasoconstrictors, such as angiotensin II. The AT1 receptor-associated protein 1 (Arap1) is expressed in vascular smooth muscle cells and increases the surface expression of the AT1-receptor in...

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Detalhes bibliográficos
Main Authors: Mederle, Katharina, Schweda, Frank, Kattler, Veronika, Doblinger, Elisabeth, Miyata, Keishi, Höcherl, Klaus, Oike, Yuichi, Castrop, Hayo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056110/
https://ncbi.nlm.nih.gov/pubmed/23844607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc12809
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