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Early treatment with IgM-enriched intravenous immunoglobulin does not mitigate critical illness polyneuropathy and/or myopathy in patients with multiple organ failure and SIRS/sepsis: a prospective, randomized, placebo-controlled, double-blinded trial

INTRODUCTION: Critical illness polyneuropathy and/or myopathy (CIPNM) is a severe complication of critical illness. Retrospective data suggest that early application of IgM-enriched intravenous immunoglobulin (IVIG) may prevent or mitigate CIPNM. Therefore, the primary objective was to assess the ef...

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Bibliografische gegevens
Hoofdauteurs:	Brunner, Richard, Rinner, Walter, Haberler, Christine, Kitzberger, Reinhard, Sycha, Thomas, Herkner, Harald, Warszawska, Joanna, Madl, Christian, Holzinger, Ulrike
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BioMed Central 2013
Onderwerpen:	Research
Online toegang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4056097/ https://ncbi.nlm.nih.gov/pubmed/24088271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13028
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Early treatment with IgM-enriched intravenous immunoglobulin does not mitigate critical illness polyneuropathy and/or myopathy in patients with multiple organ failure and SIRS/sepsis: a prospective, randomized, placebo-controlled, double-blinded trial

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