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Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock

INTRODUCTION: Septic syndromes remain the leading cause of mortality in intensive care units (ICU). Septic patients rapidly develop immune dysfunctions, the intensity and duration of which have been linked with deleterious outcomes. Decreased mRNA expressions of major histocompatibility complex (MHC...

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Bibliographic Details
Main Authors: Cazalis, Marie-Angélique, Friggeri, Arnaud, Cavé, Laura, Demaret, Julie, Barbalat, Véronique, Cerrato, Elisabeth, Lepape, Alain, Pachot, Alexandre, Monneret, Guillaume, Venet, Fabienne
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056003/
https://ncbi.nlm.nih.gov/pubmed/24321376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13150
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