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Tug-of-war of microtubule filaments at the boundary of a kinesin- and dynein-patterned surface

Intracellular cargo is transported by multiple motor proteins. Because of the force balance of motors with mixed polarities, cargo moves bidirectionally to achieve biological functions. Here, we propose a microtubule gliding assay for a tug-of-war study of kinesin and dynein. A boundary of the two m...

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Bibliographic Details
Main Authors: Ikuta, Junya, Kamisetty, Nagendra K., Shintaku, Hirofumi, Kotera, Hidetoshi, Kon, Takahide, Yokokawa, Ryuji
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055898/
https://ncbi.nlm.nih.gov/pubmed/24923426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05281
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