Liver Sinusoidal Endothelial Cell-Mediated CD8 T Cell Priming Depends on Co-Inhibitory Signal Integration over Time

The initiation of adaptive immunity requires cell-to-cell contact between T cells and antigen-presenting cells. Together with immediate TCR signal transduction, the formation of an immune synapse (IS) is one of the earliest events detected during T cell activation. Here, we show that interaction of...

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Bibliografske podrobnosti
Main Authors: Kaczmarek, Julita, Homsi, Yahya, van Üüm, Jan, Metzger, Christina, Knolle, Percy A., Kolanus, Waldemar, Lang, Thorsten, Diehl, Linda
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055751/
https://ncbi.nlm.nih.gov/pubmed/24924593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099574
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