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Functional Characterization of a Novel Family of Acetylcholine-Gated Chloride Channels in Schistosoma mansoni
Acetylcholine is the canonical excitatory neurotransmitter of the mammalian neuromuscular system. However, in the trematode parasite Schistosoma mansoni, cholinergic stimulation leads to muscle relaxation and a flaccid paralysis, suggesting an inhibitory mode of action. Information about the pharmac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055736/ https://ncbi.nlm.nih.gov/pubmed/24945827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004181 |
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