Podocytes Degrade Endocytosed Albumin Primarily in Lysosomes

Albuminuria is a strong, independent predictor of chronic kidney disease progression. We hypothesize that podocyte processing of albumin via the lysosome may be an important determinant of podocyte injury and loss. A human urine derived podocyte-like epithelial cell (HUPEC) line was used for in vitr...

Full description

Saved in:
Bibliographic Details
Main Authors: Carson, John M., Okamura, Kayo, Wakashin, Hidefumi, McFann, Kim, Dobrinskikh, Evgenia, Kopp, Jeffrey B., Blaine, Judith
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055698/
https://ncbi.nlm.nih.gov/pubmed/24924335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099771
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items