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Podocytes Degrade Endocytosed Albumin Primarily in Lysosomes
Albuminuria is a strong, independent predictor of chronic kidney disease progression. We hypothesize that podocyte processing of albumin via the lysosome may be an important determinant of podocyte injury and loss. A human urine derived podocyte-like epithelial cell (HUPEC) line was used for in vitr...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055698/ https://ncbi.nlm.nih.gov/pubmed/24924335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099771 |
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