Metabolic Impact of Anti-Angiogenic Agents on U87 Glioma Cells

BACKGROUND: Glioma cells not only secrete high levels of vascular endothelial growth factor (VEGF) but also express VEGF receptors (VEGFR), supporting the existence of an autocrine loop. The direct impact on glioma cells metabolism of drugs targeting the VEGF pathway, such as Bevacizumab (Bev) or VE...

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Autores principales: Mesti, Tanja, Savarin, Philippe, Triba, Mohamed N., Le Moyec, Laurence, Ocvirk, Janja, Banissi, Claire, Carpentier, Antoine F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055646/
https://ncbi.nlm.nih.gov/pubmed/24922514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099198
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