Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions

AMP-activated protein kinase (AMPK) is an evolutionarily conserved master regulator of metabolism and a therapeutic target in type 2 diabetes. As an energy sensor, AMPK activity is responsive to both metabolic inputs, for instance the ratio of AMP to ATP, and numerous hormonal cues. As in mammals, e...

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Bibliografiske detaljer
Main Authors: Cunningham, Katherine A., Bouagnon, Aude D., Barros, Alexandre G., Lin, Lin, Malard, Leandro, Romano-Silva, Marco Aurélio, Ashrafi, Kaveh
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055570/
https://ncbi.nlm.nih.gov/pubmed/24921650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004394
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