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PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury

Cervical spinal cord injury (SCI) damages axons and motor neurons responsible for ipsilateral forelimb function and causes demyelination and oligodendrocyte death. Inhibition of the phosphatase and tensin homologue, PTEN, promotes neural cell survival, neuroprotection and regeneration in vivo and in...

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Autores principales: Walker, Chandler L., Xu, Xiao-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055541/
https://ncbi.nlm.nih.gov/pubmed/24582904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.02.039
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