Imatinib Treatment Causes Substantial Transcriptional Changes in Adult Schistosoma mansoni In Vitro Exhibiting Pleiotropic Effects

BACKGROUND: Schistosome parasites cause schistosomiasis, one of the most important infectious diseases worldwide. For decades Praziquantel (PZQ) is the only drug widely used for controlling schistosomiasis. The absence of a vaccine and fear of PZQ resistance have motivated the search for alternative...

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Autors principals: Buro, Christin, Beckmann, Svenja, Oliveira, Katia C., Dissous, Colette, Cailliau, Katia, Marhöfer, Richard J., Selzer, Paul M., Verjovski-Almeida, Sergio, Grevelding, Christoph G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055459/
https://ncbi.nlm.nih.gov/pubmed/24921634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002923
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