Muscle Structure Influences Utrophin Expression in mdx Mice

Duchenne muscular dystrophy (DMD) is a severe muscle wasting disorder caused by mutations in the dystrophin gene. To examine the influence of muscle structure on the pathogenesis of DMD we generated mdx(4cv):desmin double knockout (dko) mice. The dko male mice died of apparent cardiorespiratory fail...

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Bibliografiske detaljer
Main Authors: Banks, Glen B., Combs, Ariana C., Odom, Guy L., Bloch, Robert J., Chamberlain, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055409/
https://ncbi.nlm.nih.gov/pubmed/24922526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004431
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