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The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity
BACKGROUND: Photoimmunotherapy (PIT) is a highly cell-selective cancer therapy, which employs monoclonal antibodies conjugated to a potent photosensitizer (mAb-IR700). Once the conjugate has bound to the target cell, exposure to near infrared (NIR) light induces necrosis only in targeted cells with...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055275/ https://ncbi.nlm.nih.gov/pubmed/24885589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-389 |
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