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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase 9 through modulation of NF-κB and AP-1 activity in human liver cancer cells

BACKGROUND AND PURPOSE: High mortality and morbidity rates for hepatocellular carcinoma in Taiwan primarily result from uncontrolled tumour metastasis. Glabridin, a prenylated isoflavonoid of licorice (Glycyrrhiza glabra) roots, is associated with a wide range of biological properties, such as regul...

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Bibliografiske detaljer
Main Authors: Hsieh, Ming-Ju, Lin, Chiao-Wen, Yang, Shun-Fa, Chen, Mu-Kuan, Chiou, Hui-Ling
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055204/
https://ncbi.nlm.nih.gov/pubmed/24641665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12626
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