Conversion to Sirolimus Ameliorates Cyclosporine-Induced Nephropathy in the Rat: Focus on Serum, Urine, Gene, and Protein Renal Expression Biomarkers

Protocols of conversion from cyclosporin A (CsA) to sirolimus (SRL) have been widely used in immunotherapy after transplantation to prevent CsA-induced nephropathy, but the molecular mechanisms underlying these protocols remain nuclear. This study aimed to identify the molecular pathways and putativ...

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Bibliographic Details
Main Authors: Sereno, José, Nunes, Sara, Rodrigues-Santos, Paulo, Vala, Helena, Rocha-Pereira, Petronila, Fernandes, João, Santos-Silva, Alice, Teixeira, Frederico, Reis, Flávio
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055143/
https://ncbi.nlm.nih.gov/pubmed/24971338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/576929
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