Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated signalling pathways

INTRODUCTION: Fibronectin (FN) is commonly used in the development of serum-free media for the expansion of mesenchymal stem cells (MSCs). This study was aimed to observe if thrombin could stimulate FN secretion by human bone marrow MSCs and investigate the potential underlying mechanisms. METHODS:...

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Detalhes bibliográficos
Main Authors: Chen, Jin, Ma, Yujie, Wang, Zi, Wang, Hengxiang, Wang, Lisheng, Xiao, Fengjun, Wang, Hua, Tan, Jianming, Guo, Zikuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055141/
https://ncbi.nlm.nih.gov/pubmed/24636778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt424
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