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Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair

The heart is a continuously pumping organ with an average lifespan of eight decades. It develops from the onset of embryonic cardiogenesis under biomechanical load, performs optimally within a defined range of hemodynamic load, and fails if acutely or chronically overloaded. Unloading of the heart l...

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Autore principale: Zimmermann, Wolfram-Hubertus
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055071/
https://ncbi.nlm.nih.gov/pubmed/24229468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt348
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