Glutathione S-transferase Mu 2-transduced mesenchymal stem cells ameliorated anti-glomerular basement membrane antibody-induced glomerulonephritis by inhibiting oxidation and inflammation

INTRODUCTION: Oxidative stress is implicated in tissue inflammation, and plays an important role in the pathogenesis of immune-mediated nephritis. Using the anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM-GN) mouse model, we found that increased expression of glutathi...

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Autori principali: Li, Yajuan, Yan, Mei, Yang, Jichen, Raman, Indu, Du, Yong, Min, Soyoun, Fang, Xiangdong, Mohan, Chandra, Li, Quan-Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055015/
https://ncbi.nlm.nih.gov/pubmed/24480247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt408
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