Inhibition of KAP1 Enhances Hypoxia-Induced Kaposi's Sarcoma-Associated Herpesvirus Reactivation through RBP-Jκ

Hypoxia-inducible factor 1α (HIF-1α) has been frequently implicated in many cancers as well as viral pathogenesis. Kaposi's sarcoma-associated herpesvirus (KSHV) is linked to several human malignancies. It can stabilize HIF-1α during latent infection and undergoes lytic replication in response...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Liming, Zhu, Caixia, Guo, Yi, Wei, Fang, Lu, Jie, Qin, Jing, Banerjee, Shuvomoy, Wang, Junwen, Shang, Hong, Verma, Subhash C., Yuan, Zhenghong, Robertson, Erle S., Cai, Qiliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054365/
https://ncbi.nlm.nih.gov/pubmed/24696491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00283-14
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