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Structure of Bacterial Transcription Factor SpoIIID and Evidence for a Novel Mode of DNA Binding

SpoIIID is evolutionarily conserved in endospore-forming bacteria, and it activates or represses many genes during sporulation of Bacillus subtilis. An SpoIIID monomer binds DNA with high affinity and moderate sequence specificity. In addition to a predicted helix-turn-helix motif, SpoIIID has a C-t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Bin, Himes, Paul, Liu, Yu, Zhang, Yang, Lu, Zhenwei, Liu, Aizhuo, Yan, Honggao, Kroos, Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054184/
https://ncbi.nlm.nih.gov/pubmed/24584501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01486-13
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