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Heterozygous Ile453Val codon mutation in exon 7, homozygous single nucleotide polymorphisms in intron 2 and 5 of cathepsin C are associated with Haim-Munk syndrome

OBJECTIVE: In the present study, we have investigated the genetic status of CTSC gene in a HMS subject, who along with her parents belonged to non-Jewish South Indian Dravidian community. MATERIALS AND METHODS: Genomic deoxyribonucleic acid isolated from the peripheral blood of the subject was ampli...

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Hlavní autoři: Aswath, Nalini, Swamikannu, Bhuminathan, Ramakrishnan, Sankar Narayanan, Shanmugam, Rajendran, Thomas, Jayakar, Ramanathan, Arvind
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054037/
https://ncbi.nlm.nih.gov/pubmed/24966751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1305-7456.126250
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