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Mutations within lncRNAs are effectively selected against in fruitfly but not in human

BACKGROUND: Previous studies in Drosophila and mammals have revealed levels of long non-coding RNAs (lncRNAs) sequence conservation that are intermediate between neutrally evolving and protein-coding sequence. These analyses compared conservation between species that diverged up to 75 million years...

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Detalhes bibliográficos
Main Authors: Haerty, Wilfried, Ponting, Chris P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053968/
https://ncbi.nlm.nih.gov/pubmed/23710818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r49
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