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DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes

BACKGROUND: Abnormal epigenetic marking is well documented in gene promoters of cancer cells, but the study of distal regulatory siteshas lagged behind.We performed a systematic analysis of DNA methylation sites connected with gene expression profilesacross normal and cancerous human genomes. RESULT...

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Autors principals: Aran, Dvir, Sabato, Sivan, Hellman, Asaf
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053839/
https://ncbi.nlm.nih.gov/pubmed/23497655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-3-r21
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