Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

BACKGROUND: Canine osteosarcoma is clinically nearly identical to the human disease, but is common and highly heritable, making genetic dissection feasible. RESULTS: Through genome-wide association analyses in three breeds (greyhounds, Rottweilers, and Irish wolfhounds), we identify 33 inherited ris...

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Detaylı Bibliyografya
Asıl Yazarlar: Karlsson, Elinor K, Sigurdsson, Snaevar, Ivansson, Emma, Thomas, Rachael, Elvers, Ingegerd, Wright, Jason, Howald, Cedric, Tonomura, Noriko, Perloski, Michele, Swofford, Ross, Biagi, Tara, Fryc, Sarah, Anderson, Nathan, Courtay-Cahen, Celine, Youell, Lisa, Ricketts, Sally L, Mandlebaum, Sarah, Rivera, Patricio, von Euler, Henrik, Kisseberth, William C, London, Cheryl A, Lander, Eric S, Couto, Guillermo, Comstock, Kenine, Starkey, Mike P, Modiano, Jaime F, Breen, Matthew, Lindblad-Toh, Kerstin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053774/
https://ncbi.nlm.nih.gov/pubmed/24330828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-12-r132
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