A computational framework for boosting confidence in high-throughput protein-protein interaction datasets

Improving the quality and coverage of the protein interactome is of tantamount importance for biomedical research, particularly given the various sources of uncertainty in high-throughput techniques. We introduce a structure-based framework, Coev2Net, for computing a single confidence score that add...

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Bibliografiske detaljer
Main Authors: Hosur, Raghavendra, Peng, Jian, Vinayagam, Arunachalam, Stelzl, Ulrich, Xu, Jinbo, Perrimon, Norbert, Bienkowska, Jadwiga, Berger, Bonnie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053744/
https://ncbi.nlm.nih.gov/pubmed/22937800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-8-r76
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