Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions

UV cross-linking and immunoprecipitation (CLIP) and individual-nucleotide resolution CLIP (iCLIP) are methods to study protein-RNA interactions in untreated cells and tissues. Here, we analyzed six published and two novel data sets to confirm that both methods identify protein-RNA cross-link sites,...

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Detalhes bibliográficos
Main Authors: Sugimoto, Yoichiro, König, Julian, Hussain, Shobbir, Zupan, Blaž, Curk, Tomaž, Frye, Michaela, Ule, Jernej
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053741/
https://ncbi.nlm.nih.gov/pubmed/22863408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-8-r67
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